should I loan money to my daughter and son-in-law?

My daughter is a doctor, son-in-law is a pharmacist but has a business which seems not doing too well because of high debts. He could earn more by working as a pharmacist but insists on having the buisness since he likes its flexibility. My daughter works as a doctor so her income is much higher so she wants to help him financially. Besides her own savings, she asks me to lend her money so she can help him to pay off the mortgage (on the unit he bought before the marriage) sooner. Should I lend money to her or not? I am a retiree of average financial means.

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