Home loan interest rate – was I quoted wrong?

My husband and I are buying a home. The home we are looking at is about $ 73,000. We were quoted a 6.25% interest rate for a 30 year note with a monthly payment of $ 908 (without tti). This seemed quite excessive to me. Coming home and doing the calculations (on bankrate.com’s mortgage calculator), a 30 year note of $ 73,000 with a 6.25% interest rate should result in a $ 450 monthly payment. In order to get my monthly payment up to $ 908, I had to make my interest rate 14.75%. Now, the underwriter said the 6.25% wasn’t the APR. What does that mean? Why would I have two interest rates, and why is one so much higher than the other? If we pay $ 908 a month, we end up paying $ 326,000 for a $ 78,000 home. This seems a little ludicrous to me. Anyone with financial experience got any wisdom to share?
This was just the man who’s selling me the house who will put everything together for the loan application. The total including TTI was $ 1208.

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